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DNA, siRNA, miRNA, mRNA,shRNA | Lung, spleen, systemic | in vivo ready-to-use cationic polymer solution for: in vivo functional study, oncology therapy, DNA vaccination/immunization
Reagent | in vivo-jetPEI® |
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Molecule delivered | DNA |
Applications | in vivo functional studies (overexpression, knock-down, CRISPR genome editing) |
Targeted organs | All organs |
Injection routes | Various systemic and local administration routes |
Number of transfections | eg. 100 µl of in vivo-jetPEI® delivery reagent is sufficient to perform 15 to 25 intravenous injections in mouse. |
Storage | Store in vivo-jetPEI® at -20 ± 5 °C. |
Provided with | 10% glucose solution |
in vivo-jetPEI® is the most advanced in vivo transfection reagent for safe and efficient in vivo delivery of DNA, si/miRNA and other oligonucleotides in animal models. With a track record of over 700 publications, in vivo-jetPEI® is the consensual in vivo transfection method for in vivo functional studies, cancer research and immunization/vaccination.
Table 1: Range of in vivo-jetPEI® quality grade reagents for each step of in vivo DNA, si/miRNA transfection. in vivo-jetPEI® is available as an R&D grade for fundamental research and proof of concept studies. For preclinical biodistribution and toxicology studies and early phase clinical studies, we supply a higher preclinical grade in vivo-jetPEI®. GMP in vivo-jetPEI® is the highest quality grade available to meet quality demands in Human clinical trials.
Reference Number | Amount of reagent | Amount of 10% glucose solution |
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101000040 | in vivo-jetPEI® 0.1 mL | 10 ml |
101000030 | in vivo-jetPEI® 0.5 mL | 2 x 10 ml |